Journal article
ISMRM Annual Meeting
Assistant Professor
APA
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Wu, C., Yankeelov, T., & Virostko, J. Reduced Field-of-View Intravoxel Incoherent Motion of the Human Pancreas Reflects Biphasic Response to Glucose Ingestion. ISMRM Annual Meeting.
Chicago/Turabian
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Wu, Chengyue, T. Yankeelov, and John Virostko. “Reduced Field-of-View Intravoxel Incoherent Motion of the Human Pancreas Reflects Biphasic Response to Glucose Ingestion.” ISMRM Annual Meeting (n.d.).
MLA
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Wu, Chengyue, et al. “Reduced Field-of-View Intravoxel Incoherent Motion of the Human Pancreas Reflects Biphasic Response to Glucose Ingestion.” ISMRM Annual Meeting.
BibTeX Click to copy
@article{chengyue-a,
title = {Reduced Field-of-View Intravoxel Incoherent Motion of the Human Pancreas Reflects Biphasic Response to Glucose Ingestion},
journal = {ISMRM Annual Meeting},
author = {Wu, Chengyue and Yankeelov, T. and Virostko, John}
}
Monitoring of the pancreatic islet is needed to assess individuals at risk for developing diabetes and facilitate development of islet-directed therapies. Pancreatic islets may be detectable due to their high vascularity. We imaged pancreas perfusion using both whole field-of-view and reduced field-of-view Intravoxel Incoherent Motion (IVIM) and found that the reduced field-of-view technique achieved similar image quality in half the time. We then performed a reduced field-of-view IVIM acquisition on four healthy controls. We found that pancreas perfusion increased dynamically in response to oral glucose challenge, exhibiting a biphasic increase that parallels the time course of insulin secretion.